منابع مشابه
Primary Mediastinal Large B-cell Lymphoma
Primary mediastinal large B-cell lymphoma (PMLBCL) is a distinct disease entity that has a relatively short history. The prognosis and therapy of patients with PMLBCL is still controversial. We summarize our experience with PMLBCL at the Medical University of South Carolina between 1997 and 2000.
متن کاملPrimary Mediastinal B Large Cell Lymphoma
Primary mediastinal large B cell lymphoma (PMLBCL) has been recognized as a specific subtype of diffuse large B cell lymphoma with characteristic clinical, pathological and biological features. This paper presents a diagnostic and therapeutic approach in the treatment of patient with this disease. A patient aged 35 years visited a doctor because of the presence of B-symptoms and signs of the ex...
متن کاملPrimary Mediastinal Large B-Cell Lymphoma
Correspondence: Kerry J. Savage, M.D., M.Sc., F.R.C.P.C., British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia, Canada. Telephone: 604-877-6000; Fax: 604-877-0585; e-mail: [email protected] Received February 1, 2006; accepted for publication February 22, 2006. ©AlphaMed Press 1083-7159/2006/$20.00/0 Abstract Primary mediastinal large B-cell lymphoma represents ...
متن کاملPrimary mediastinal B-cell lymphoma.
Primary mediastinal B-cell lymphoma is a discrete clinicopathologic entity. Molecular analysis reveals it to be distinct from other types of large B-cell lymphoma, and retrospective analysis suggests that it may respond better to multi-agent chemotherapy regimens than to the more commonly used CHOP. The addition of rituximab may mitigate such differences, and may also diminish the role of conso...
متن کاملConstitutive STAT6 activation in primary mediastinal large B-cell lymphoma.
Primary mediastinal large B-cell lymphoma (PMBL), currently recognized as a diffuse large B-cell lymphoma (DLBCL) subtype, shows increased expression of interleukin 4 (IL-4)/IL-13 signaling effectors and targets, suggesting constitutive activation of these pathways. We therefore investigated the functional state of the signal transducer and activator of transcription 6 (STAT6), mediating IL-4/I...
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ژورنال
عنوان ژورنال: Praxis medica
سال: 2019
ISSN: 0350-8773,2560-3310
DOI: 10.5937/pramed1901049k